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Continuous exercise induces airway epithelium damage while a matched-intensity and volume intermittent exercise does not

Abstract : Background: While continuous exercise (CE) induces greater ventilation (_ V E) when compared to intermittent exercise (IE), little is known of the consequences on airway damage. Our aim was to investigate markers of epithelial cell damage-i.e. serum levels of CC16 and of the CC16/SP-D ratio-during and following a bout of CE and IE of matched work. Methods: Sixteen healthy young adults performed a 30-min continuous (CE) and a 60-min intermittent exercise (IE; 1-min work: 1-min rest) on separate occasions in a random order. Intensity was set at 70% of their maximum work rate (WR max). Heart rate (HR) and _ V E were measured throughout both tests. Blood samples were taken at rest, after the 10th min of the warm-up, at the end of both exercises, half way through IE (matched time but 50% work done for IE) as well as 30-and 60-min post-exercise. Lactate and CC16 and SP-D were determined.
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https://hal.univ-cotedazur.fr/hal-02557315
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Submitted on : Tuesday, April 28, 2020 - 4:34:20 PM
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Adrien Combes, Jeanne Dekerle, Xavier Dumont, Rosie Twomey, Alfred Bernard, et al.. Continuous exercise induces airway epithelium damage while a matched-intensity and volume intermittent exercise does not. Respiratory Research, BioMed Central, 2019, 20, pp.12. ⟨10.1186/s12931-019-0978-1⟩. ⟨hal-02557315⟩

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