Effect of rehabilitation and botulinum toxin injection on gait in chronic stroke patients: A randomized controlled study - Université Côte d'Azur
Journal Articles Journal of Rehabilitation Medicine Year : 2015

Effect of rehabilitation and botulinum toxin injection on gait in chronic stroke patients: A randomized controlled study

Abstract

Background: Botulinum toxin injections are used to treat spasticity in stroke. Although this treatment is effective on muscle tone, its effect on functional gait-related activities remains uncertain. Objective: The aim of this randomized controlled trial was to determine the effect of a self-rehabilitation programme as an adjunct to botulinum toxin injections on gait-related activities in patients with chronic hemiparesis. Methods: Thirty-five outpatients were included. Each patient was randomized to 1 of 2 groups: botulinum toxin + standardized self-rehabilitation programme (R group, n = 19) or botulinum toxin alone (C group, n = 16). Each patient was evaluated with the following tests before botulinum toxin injections and one month afterwards: 10-m timed walk, Timed Up and Go, distance covered in 6 min over an ecological circuit, and the stair test. Results: There were significant improvements in the R group compared with the C group: maximal gait speed improved by 8% (p = 0.003); distance covered in 6 min over an ecological circuit increased by 7.1% (p = 0.01); and time to ascend and to descend a flight of stairs decreased by 9.8% (p = 0.003) and 6.6% (p = 0.009), respectively. The self-rehabilitation programme was well tolerated and safe. Conclusion: These results strongly suggest that a standardized self-rehabilitation programme constitutes a useful adjunct to botulinum toxin injections in order to improve gait-related activities
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hal-02528995 , version 1 (08-06-2021)

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N. Roche, R. Zory, A Sauthier, C Bonnyaud, D Pradon, et al.. Effect of rehabilitation and botulinum toxin injection on gait in chronic stroke patients: A randomized controlled study. Journal of Rehabilitation Medicine, 2015, 47 (1), pp.31-37. ⟨10.2340/16501977-1887⟩. ⟨hal-02528995⟩
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