R. H. Arnardottir, G. Boman, K. Larsson, H. Hedenstro, and M. Emtner, Interval training compared with continuous training in patients with COPD, Respir Med, vol.101, issue.6, pp.1196-204, 2007.

A. W. Midgley and L. R. Mc-naughton, Time at or near VO 2 max during continuous and intermittent running. A review with special reference to considerations for the optimisation of training protocols to elicit the longest time at or near VO 2 max, J Sports Med Phys Fitness, vol.46, issue.1, pp.1-14, 2006.

A. W. Midgley, L. R. Mcnaughton, and A. M. Jones, Training to enhance the physiological determinants of long-distance running performance: can valid recommendations be given to runners and coaches based on current scientific knowledge, Sports Med, vol.37, issue.10, pp.857-80, 2007.

J. S. Ramos, L. C. Dalleck, A. E. Tjonna, K. S. Beetham, and J. S. Coombes, The impact of high-intensity interval training versus moderate-intensity continuous training on vascular function: a systematic review and meta-analysis, Sports Med, vol.45, issue.5, pp.679-92, 2015.

A. R. Morton, A. G. Hahn, and K. D. Fitch, Continuous and intermittent running in the provocation of asthma, Ann Allergy, vol.48, issue.2, pp.123-132, 1982.

S. Sabapathy, R. A. Kingsley, D. A. Schneider, L. Adams, and N. R. Morris, Continuous and intermittent exercise responses in individuals with chronic obstructive pulmonary disease, Thorax, vol.59, issue.12, pp.1026-1057, 2004.

N. A. Smart, G. Dieberg, and F. Giallauria, Intermittent versus continuous exercise training in chronic heart failure: a meta-analysis, Int J Cardiol, vol.166, issue.2, pp.352-360, 2013.

A. Combes, J. Dekerle, N. Webborn, P. Watt, V. Bougault et al., Exerciseinduced metabolic fluctuations influence AMPK, p38-MAPK and CaMKII phosphorylation in human skeletal muscle, Physiol Rep, vol.3, issue.9, 2015.
URL : https://hal.archives-ouvertes.fr/hal-02390518

D. Jimenez-pavon and C. J. Lavie, High-intensity intermittent training versus moderate-intensity intermittent training: is it a matter of intensity or intermittent efforts?, Br J Sports Med, vol.51, issue.18, pp.1319-1339, 2017.

M. R. Bonsignore, G. Morici, L. Riccobono, G. Insalaco, A. Bonanno et al., Airway inflammation in nonasthmatic amateur runners, Am J Physiol Lung Cell Mol Physiol, vol.281, issue.3, pp.668-76, 2001.

K. H. Carlsen, G. Engh, and M. Mork, Exercise-induced bronchoconstriction depends on exercise load, Respir Med, vol.94, issue.8, pp.750-755, 2000.

P. E. Brockmann, J. A. Castro-rodriguez, N. L. Holmgren, J. Cerda, M. Contreras et al., Urinary leukotriene excretion profile in children with exercise-induced asthma compared with controls: a preliminary study, Allergol Immunopathol (Madr), vol.40, issue.3, pp.181-187, 2012.

T. S. Hallstrand, M. W. Moody, M. L. Aitken, and W. R. Henderson, Airway immunopathology of asthma with exercise-induced bronchoconstriction, J Allergy Clin Immunol, vol.16, issue.3, pp.586-93, 2005.

P. Kippelen, J. Larsson, S. D. Anderson, J. D. Brannan, B. Dahlen et al., Effect of sodium cromoglycate on mast cell mediators during hyperpnea in athletes, Med Sci Sports Exerc, vol.42, issue.10, pp.1853-60, 2010.

J. P. Parsons, C. P. Baran, G. Phillips, D. Jarjoura, C. Kaeding et al., Airway inflammation in exerciseinduced bronchospasm occurring in athletes without asthma, J Asthma, vol.45, issue.5, pp.363-370, 2008.

E. Tufvesson, H. Svensson, J. Ankerst, and L. Bjermer, Increase of club cell (Clara) protein (CC16) in plasma and urine after exercise challenge in asthmatics and healthy controls, and correlations to exhaled breath temperature and exhaled nitric oxide, Respir Med, vol.107, issue.11, pp.1675-81, 2013.

C. Bolger, E. Tufvesson, S. D. Anderson, G. Devereux, J. G. Ayres et al., Effect of inspired air conditions on exercise-induced bronchoconstriction and urinary CC16 levels in athletes, J Appl Physiol, vol.111, pp.1059-65, 2011.

C. Bolger, E. Tufvesson, M. Sue-chu, G. Devereux, J. G. Ayres et al., Hyperpnea-induced bronchoconstriction and urinary CC16 levels in athletes, Med Sci Sports Exerc, vol.43, pp.1207-1220, 2011.

S. Carbonnelle, M. Francaux, I. Doyle, X. Dumont, C. De-burbure et al., Changes in serum pneumoproteins caused by shortterm exposures to nitrogen trichloride in indoor chlorinated swimming pools, Biomarkers, vol.7, issue.6, pp.464-78, 2002.

L. Chimenti, G. Morici, A. Paternò, R. Santagata, A. Bonanno et al., Bronchial epithelial damage after a half-marathon in nonasthmatic amateur runners, Am J Physiol Lung Cell Mol Physiol, vol.298, pp.857-62, 2010.

P. Kippelen and S. D. Anderson, Airway injury during high-level exercise, Br J Sports Med, vol.46, issue.6, pp.385-90, 2012.

A. Bernard, Critical review of Clara cell protein: sound science?, Biomarkers, vol.13, issue.3, pp.237-280, 2008.

E. T. Howley, D. R. Bassett, and H. G. Welch, Criteria for maximal oxygen uptake: review and commentary, Med Sci Sports Exerc, vol.27, issue.9, pp.1292-301, 1995.

K. Wasserman, B. J. Whipp, and S. N. Koyal, Anaerobic Threshold BWL. Respiratory gas-exchange during exercise, J Appl Physiol, vol.35, issue.2, pp.236-279, 1973.

W. L. Beaver, K. Wasserman, and B. J. Whipp, A new method for detecting Anaerobic Threshold by gas-exchange, J Appl Physiol, vol.60, issue.6, pp.2020-2027, 1986.

B. Gandevia, H. , and P. , Terminology for measurements of ventilatory capacity; a report to the thoracic society, Thorax, vol.12, issue.4, pp.290-293, 1957.

C. Hermans, O. Aly, B. I. Nyberg, C. Peterson, and A. Bernard, Determinants of Clara cell protein (CC16) concentration in serum: a reassessment with two different immunoassays, Clin Chim Acta, vol.272, issue.2, pp.101-111, 1998.

A. Blomberg, I. Mudway, M. Svensson, A. Hagenbjörk-gustafsson, L. Thomasson et al., Clara cell protein as a biomarker for ozone-induced lung injury in humans, Eur Respir J, vol.22, pp.883-891, 2003.

E. V. Bräuner, J. Mortensen, P. Møller, A. Bernard, P. Vinzents et al., Effects of ambient air particulate exposure on blood-gas barrier permeability and lung function, Inhal Toxicol, vol.21, pp.38-47, 2009.

F. Broeckaert, K. Arsalane, C. Hermans, E. Bergamaschi, A. Brustolin et al., Serum clara cell protein: a sensitive biomarker of increased lung epithelium permeability caused by ambient ozone, Environ Health Perspect, vol.108, pp.533-540, 2000.

L. Font-ribera, M. Kogevinas, J. P. Zock, F. P. Gomez, E. Barreiro et al., Short-term changes in respiratory biomarkers after swimming in a chlorinated pool, Environ Health Perspect, vol.118, issue.11, pp.1538-1582, 2010.

E. C. Gomes, V. Stone, F. , and G. , Impact of heat and pollution on oxidative stress and CC16 secretion after 8 km run, Eur J Appl Physiol, vol.111, issue.9, pp.2089-97, 2011.

C. J. Nanson, J. L. Burgess, M. Robin, and A. M. Bernard, Exercise alters serum pneumoprotein concentrations, Respir Physiol, vol.127, issue.2-3, pp.259-65, 2001.

B. Boukelia, M. C. Fogarty, R. C. Davison, and F. Gd, Diurnal physiological and immunological responses to a 10-km run in highly trained athletes in an environmentally controlled condition of 6°C, Eur J Appl Physiol, vol.117, pp.1-6, 2017.

K. Romberg, L. Bjermer, and E. Tufvesson, Exercise but not mannitol provocation increases urinary Clara cell protein (CC16) in elite swimmers, Respir Med, vol.105, issue.1, pp.31-37, 2011.

K. C. Beck, Control of airway function during and after exercise in asthmatics, Med Sci Sports Exerc, vol.31, issue.1suppl, pp.4-11, 1999.

K. C. Beck, K. P. Offord, and P. D. Scanlon, Bronchoconstriction occurring during exercise in asthmatic subjects, Am J Respir Crit Care Med, vol.149, pp.352-359, 1994.

C. O'neill, K. Burgomaster, O. Sanchez, and S. Dogra, The acute response to interval and continuous exercise in adults with confirmed airway hyperresponsiveness, J Sci Med Sport, vol.20, pp.976-80, 2017.

V. Bougault, J. Turmel, J. St-laurent, M. Bertrand, and L. P. Boulet, Asthma, airway inflammation and epithelial damage in swimmers and cold-air athletes, Eur Respir J, vol.33, pp.740-746, 2009.